CROI 2025 - CROI 2025

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"Welcome and Session Overview for the Scott M. Hammer Workshop for New Investigators and Trainees" by

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"Virology: State of the Art and Navigating Presentations at CROI 2025" by Stuart J.D. Neil King's College London, London, UK

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"Immunology: State of the Art and Navigating Presentations at CROI 2025" by Lishomwa Ndhlovu Weill Cornell Medicine, New York, NY, USA

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"Prevention of HIV and STIs: State of the Art and Navigating Presentations at CROI 2025" by Susan P. Buchbinder San Francisco Department of Public Health, San Francisco, CA, USA

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"HIV Treatment and Complications of HIV Disease: State of the Art and Navigating Presentations at CROI 2025" by Judith S. Currier University of California Los Angeles, Los Angeles, CA, USA

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"HIV Cure Research: State of the Art and Navigating Presentations at CROI 2025" by Joseph J. Eron, Jr University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Workshop: Scott M. Hammer Workshop for New Investigators and Trainees

"Message to New Investigators" by

Workshop: Case-Based Workshop on the Liver and Its Complications

"Liver Steatosis: New Nomenclature, New Tests, and New Drugs" by Mandana Khalili University of California San Francisco, San Francisco, CA, USA

Workshop: Case-Based Workshop on the Liver and Its Complications

"Hepatitis B in the Gray Zone: Personalizing Treatment and Monitoring" by Paul Y. Kwo Stanford University, Stanford, CA, USA

Workshop: Case-Based Workshop on the Liver and Its Complications

"Liver Cancer Surveillance: Who, How, When, and For How Long" by Fasiha Kanwal Baylor College of Medicine, Houston, TX, USA

Workshop: Case-Based Workshop on the Liver and Its Complications

"Discussion with Audience Questions and Answers" by

Workshop: Clinical Trial Design and Analysis

"Using Machine Learning to Focus HIV Prevention Interventions" by Carlos S. Saldana Emory University, Atlanta, GA, USA

Workshop: Clinical Trial Design and Analysis

"HIV Prevention Efficacy Trial Design: Lessons From Recent Trials" by Holly Janes Fred Hutchinson Cancer Center, Seattle, WA, USA

Workshop: Clinical Trial Design and Analysis

"How Much Is Enough: The Importance of Pharmacokinetic Targets" by Paolo Denti University of Cape Town, Cape Town, South Africa

Workshop: Frontiers in Laboratory Technologies

"Breaking the HIV Capsid: Atomic Force Microscopy Visualization" by Juan R. Perilla University of Delaware, Newark, DE, USA

Workshop: Frontiers in Laboratory Technologies

"Advances in Single-Cell Multiomic Profiling and Its Use in Virology and Immunology" by Alexander Marson University of California San Francisco, San Francisco, CA, USA

Workshop: Frontiers in Laboratory Technologies

"Visualizing Tissues: State-of-the-Art Single-Cell 3D Spatial Transcriptomics" by Nikolaus Rajewsky Berlin Institute for Medical Systems Biology, Berlin, Germany

Workshop: Frontiers in Laboratory Technologies

"Advances in CRISPR-Cas Editing Methods and Their Use in Virology and Immunology" by Angela R. Wahl University of Alabama at Birmingham, Birmingham, AL, USA

Workshop: Workshop on Antiretroviral Therapy: Case-Based Panel Discussion

"Case Presentations With Panel Discussion, Plus Questions and Answers From the Audience" by Jose R. Arribas Hospital La Paz Institute for Health Research, Madrid, Spain

Rachel A. Bender Ignacio University of Washington, Seattle, WA, USA

Cecilia Kanyama UNC Project, Lilongwe. Malawi

Juan Sierra-Madero Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubiran, Mexico City, Mexico

Oana Sandulescu Carol Davila University of Medicine and Pharmacy, București, Romania

Opening Session

"Welcome from the Conference Chair" by Diane V. Havlir University of California San Francisco, San Francisco, CA, USA

Opening Session

"Introduction to the Bernard Fields Lecture" by Katharine J. Bar University of Pennsylvania, Philadelphia, PA, USA

Opening Session

"Bernard Fields Lecture: How Integration Site Analyses Inform HIV Pathogenesis, Persistence, and Gene Therapy" by Frederic D. Bushman University of Pennsylvania, Philadelphia, PA, USA

Opening Session

"Introduction to the Martin Delaney Presentation" by Dawn Averitt The Well Project, Women's Research Initiative on HIV/AIDS, South Strafford, VT, USA

Opening Session

"Martin Delaney Presentation: 40+ Years of HIV: What’s Changed, What Hasn’t, What Shouldn’t, What Must" by Rebecca Denison Woman Organized to Respond to Life-threatening Diseases (WORLD), Berkeley, CA, USA

Opening Session

"Introduction to the N'Galy-Mann Lecture" by Wafaa M. El-Sadr ICAP at Columbia University, New York, NY, USA

Opening Session

"N'Galy-Mann Lecture: When Science Alone is Not Enough: The Intersection of Drug Use, Public Health, and Policy" by Adeeba Kamarulzaman Monash University Malaysia, Kuala Lumpur, Malaysia

Opening Session

"Special Presentation by the San Francisco Gay Men's Chorus" by

Opening Session

"Opening Session Conclusion and Welcome to the Opening Reception" by Nicolas Chomont Université de Montréal, Montreal, Canada

Monday Plenary Session

"CROI Program Committee Chair Welcome to Monday" by Diane V. Havlir University of California San Francisco, San Francisco, CA, USA

Monday Plenary Session

"HIV Cure: A Translational Research Perspective" by Ole Søgaard Aarhus University, Aarhus, Denmark

Monday Plenary Session

"The Global HIV/AIDS Pandemic: Where Are We Now?" by Chris Beyrer Duke Global Health Institute, Durham, NC, USA

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Introduction of Speakers Part 1" by

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Comparing Empirical HIV Incidence With UNAIDS Estimated Incidence Declines in Sub-Saharan Africa" by Oliver Stevens Imperial College London, London, UK

Oral Abstract: Evolution of HIV and Mpox Epidemics

"All-Cause and Cause-Specific Mortality Trends Among Persons With and Without HIV in Rural Tanzania" by Julie Ambia University of Bristol, Bristol, UK

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Associations of Dolutegravir and the COVID-19 Pandemic on Viral Suppression in South African Adults" by Haroon Moolla University of Cape Town, Cape Town, South Africa

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Questions and Answers Part 1" by

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Introduction of Speakers Part 2" by

Oral Abstract: Evolution of HIV and Mpox Epidemics

"A Multistage Sampling Approach to Refine HIV Mortality Estimates in KwaZulu-Natal, South Africa" by Alastair VanHeerden Human Sciences Research Council, Pretoria, South Africa

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Genotypic Characterization of Mpox and a Tale of 2 Co-Circulating Viruses in Uganda" by Nicholas Bbosa London School of Hygiene & Tropical Medicine, London, UK

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Characterization of Mpox Cases in Uganda: Diversity of the Confirmed Cases" by Ritah Namusoosa Ministry of Health Uganda, Kampala, Uganda

Oral Abstract: Evolution of HIV and Mpox Epidemics

"Questions and Answers Part 2" by

Oral Abstract: HIV Reservoirs and Cure Strategies

"Introduction of Speakers Part 1" by

Oral Abstract: HIV Reservoirs and Cure Strategies

"5’Leader Defects in HIV Plasma Clones Drive 80% of Persistent Viremia on Long-Term ART" by Francesco R. Simonetti The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Oral Abstract: HIV Reservoirs and Cure Strategies

"BACH2-Driven Tissue Resident Memory Programs Promote HIV-1 Persistence" by Yulong Wei Yale University, New Haven, CT, USA

Oral Abstract: HIV Reservoirs and Cure Strategies

"Longitudinal Co-Evolution of HIV-1 Reservoir Cells and Immune Effector Cells During Long-Term Art" by Weiwei Sun Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA

Oral Abstract: HIV Reservoirs and Cure Strategies

"AZD5582 and Venetoclax Reduce SIV Reservoirs in ART-Suppressed Macaques" by Benedicth Ukhueduan Emory University, Atlanta, GA, USA

Oral Abstract: HIV Reservoirs and Cure Strategies

"Questions and Answers Part 1" by

Oral Abstract: HIV Reservoirs and Cure Strategies

"Introduction of Speakers Part 2" by

Oral Abstract: HIV Reservoirs and Cure Strategies

"HIV GAG x CD3 Soluble TCR Bispecific Reduces the Active HIV Reservoir in a Phase I/II Trial" by Beatriz Mothe Fundació Lluita contra la SIDA, Badalona, Spain

Oral Abstract: HIV Reservoirs and Cure Strategies

"Evaluation of 2 bNAbs Plus Vesatolimod in Early-Treated South African Women With HIV-1 During ATI" by Thumbi Ndung'u Africa Health Research Institute, Mtubatuba, South Africa

Oral Abstract: HIV Reservoirs and Cure Strategies

"A Single Infusion of CCR5-/- CD4 Tscm Cells Promotes Control of SIV Upon ATI" by Ashish A. Sharma Emory University, Atlanta, GA, USA

Oral Abstract: HIV Reservoirs and Cure Strategies

"RIO: A Randomised Placebo-Controlled Study of 2 LS-bNAbs in People Treated in Early HIV" by Sarah Fidler Imperial College London, London, UK

Oral Abstract: HIV Reservoirs and Cure Strategies

"Questions and Answers Part 2" by

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Introduction of Speakers Part 1" by

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Maternal Tenofovir Prophylaxis With Active Immunization to Prevent Infant Hepatitis B" by Gonzague Jourdain Chiang Mai University, Chiang Mai, Thailand

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Efficacy of Home Visits for Pregnant Couples to Promote Couple HIV Testing and Family Health" by Lynae Darbes University of Michigan, Ann Arbor, MI, USA

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Dolutegravir Does Not Reduce Levonorgestrel or Medroxyprogesterone Acetate Concentrations in WLWH" by Rebecca Ryan Botswana Harvard AIDS Institute Partnership, Gabarone, Botswana

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Lenacapavir Pharmacokinetics, Safety, and Efficacy in Adolescents and Adults in PURPOSE 1" by Katherine Gill Desmond Tutu HIV Foundation, Cape Town, South Africa

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Questions and Answers Part 1" by

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Introduction of Speakers Part 2" by

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Assessing IIT and Mortality Among CLHIV <15 yo in PEPFAR-Supported Countries, FY21 - FY24" by Michelle Yang US Department of State, Washington, DC, USA

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Multidose PK/Safety of Dolutegravir Dispersible Tablets & Oral Films in Neonates: PETITE-DTG Study" by Adrie Bekker Stellenbosch University, Cape Town, South Africa

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Genotypic Resistance in the African Paediatric CHAPAS-4 Trial of Second-Line Antiretroviral Therapy" by Alasdair Bamford Great Ormond Street NHS Foundation Trust, London, UK

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Abemaciclib, a CDK4/6 Inhibitor, in HIV-Associated and HIV-Negative Kaposi Sarcoma" by Jose R. Mercado-Matos National Cancer Institute, Bethesda, MD, USA

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Differences in Treatment and Overall Survival in People With and Without HIV and Oropharynx Cancer" by Elizabeth Chiao University of Texas MD Anderson Cancer Center, Houston, TX, USA

Oral Abstract: Maternal-Child Health and Treatment of Malignancies

"Questions and Answers Part 2" by

Oral Abstract: The Coinfections: Hepatitis and TB

"Introduction of Speakers Part 1" by

Oral Abstract: The Coinfections: Hepatitis and TB

"Trends in Hepatitis C Virus (HCV) Infection Incidence Among PWH Engaged in Care in the US: 1995-2023" by Yotam Arens Weill Cornell Medicine, New York, NY, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"HIV Decreases Both Hepatitis B Antibody Titer and Neutralization After Spontaneous HBV Control" by Chloe Thio The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"HBV Care Continuum and Associated Factors in Rwanda: A Population-Based Study From 2016-2023" by Jean Damascene Makuza University of British Columbia, Vancouver, Canada

Oral Abstract: The Coinfections: Hepatitis and TB

"Intrahepatic Transcriptomics in HBV-HIV Co-Infection Uncover Host Responses to HBV Transcription" by Che-Min Lo The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"Questions and Answers Part 1" by

Oral Abstract: The Coinfections: Hepatitis and TB

"Introduction of Speakers Part 2" by

Oral Abstract: The Coinfections: Hepatitis and TB

"Highly Durable Seroprotection With HepB-CpG Vaccine in People With HIV (PWH): ACTG A5379 (BEeHIVe)" by Kristen Marks Weill Cornell Medicine, New York, NY, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"Epigenetic Age Predictors of Semaglutide-Related Liver Fat Changes in People With HIV" by Alina Pang Weill Cornell Medicine, New York, NY, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"Supplemental High-Dose Rifampicin and Levofloxacin for Inpatients With Disseminated HIV-TB" by Graeme Meintjes University of Cape Town, Cape Town, South Africa

Oral Abstract: The Coinfections: Hepatitis and TB

"Casual Contact in Community Settings Explains Majority of TB Transmission in South Africa" by Neel R. Gandhi Emory University, Atlanta, GA, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"DOLPHIN-Moms: Pharmacokinetics of Dolutegravir and HIV Viral Suppression With 1HP or 3HP in Pregnancy" by Jyoti Mathad Weill Cornell Medicine, New York, NY, USA

Oral Abstract: The Coinfections: Hepatitis and TB

"Questions and Answers Part 2" by

Themed Discussion: Down But Not Out: Elite Control of HIV

"Session Overview" by Javier Martinez-Pìcado IrsiCaixa, Badalona, Spain

Themed Discussion: Down But Not Out: Elite Control of HIV

"Effect of ART Start Time, ART Duration, and Elite Control on HIV Transcription" by Adam Wedrychowski San Francisco VA Medical Center, San Francisco, CA, USA

Themed Discussion: Down But Not Out: Elite Control of HIV

"Viral Reservoir Characteristics in Lymphoid Tissues of HIV-1 Elite Controllers" by Samantha K. Marzi Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA

Themed Discussion: Down But Not Out: Elite Control of HIV

"CD8+ T Cells Shape the HIV Integration Site Landscape According to the Degree of T-Cell Pressure" by R. Bradley Jones Weill Cornell Medicine, New York, NY, USA

Themed Discussion: Down But Not Out: Elite Control of HIV

"Anti-IL-10/Anti-PD-1 Dual Blockade Leads to IFN-Related HIV Elite Control Signatures" by Susan P. Ribeiro Emory University, Atlanta, GA, USA

Themed Discussion: Down But Not Out: Elite Control of HIV

"Loss of Virological Control 32 Years After HIV-1 Diagnosis in an Exceptional Elite Controller" by Anna Pons-Grífols IrsiCaixa, Badalona, Spain

Themed Discussion: Down But Not Out: Elite Control of HIV

"Discussion with Audience Q&A" by

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Session Overview" by Anoop Shah London School of Hygiene & Tropical Medicine, London, UK

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Mitochondrial Haplogroups and Left Ventricular Dysfunction in People Living With and Without HIV" by Craig Cronin The Johns Hopkins Hospital, Baltimore, MD, USA

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Sex Differences in Myocardial Steatosis in South African Youth With Perinatally-Acquired HIV" by Morne Kahts University of Cape Town, Cape Town, South Africa

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Physician-Confirmed Incident Heart Failure Phenotypes and Etiologies Within CNICS" by Matthew J. Feinstein Northwestern University, Chicago, IL, USA

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Readmission Risk for Adults With HIV Hospitalized for Heart Failure or Acute Myocardial Infarction" by Ping Yang The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Heart Failure Among People With HIV: Prescription of Guideline-Directed Medical Therapy" by Melissa K. Cutshaw Duke University School of Medicine, Durham, NC, USA

Themed Discussion: Heart Failure: Hiding in Plain Sight

"Discussion with Audience Q&A" by

Themed Discussion: HIV Self-Testing: Here and Now

"Session Overview" by Mateo Prochazka World Health Organization, Geneva, Switzerland

Themed Discussion: HIV Self-Testing: Here and Now

"National HIV Self-Test Distribution Program: HIV Testing, Diagnosis and Treatment, 3/2023 - 5/2024" by Patrick S. Sullivan Emory University, Atlanta, GA, USA

Themed Discussion: HIV Self-Testing: Here and Now

"Estimating Need for Annual HIV Testing Met by a Nationwide Mailed HIV Self-Testing Program" by Jen Hecht

Themed Discussion: HIV Self-Testing: Here and Now

"Moderators of a Home-Based Couple Intervention on Couple HIV Testing and Counselling Uptake in Kenya" by Zachary A. Kwena Kenya Medical Research Institute-UCSF Infectious Disease Research Training Program, Kisumu, Kenya

Themed Discussion: HIV Self-Testing: Here and Now

"Discussion with Audience Q&A" by

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Session Overview" by James A. Hoxie University of Pennsylvania, Philadelphia, PA, USA

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Validation of Quantification of Lesional KSHV DNA Content for Diagnosis of Kaposi Sarcoma in Africa" by Aggrey Semeere Infectious Diseases Institute, Kampala, Uganda

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Impact of Low-Dose Intra-Lesional Nivolumab for Kaposi Sarcoma on T-Cell Proliferation and Function" by Chia-Ching Wang University of California San Francisco, San Francisco, CA, USA

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Immunologic Responses to Pomalidomide and Liposomal Doxorubicin for Kaposi Sarcoma Treatment" by Matthew Witterholt National Cancer Institute, Bethesda, MD, USA

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Causes of Death Among Adults With HIV-Associated Kaposi Sarcoma in East Africa in the Treat All Era" by Helen Byakwaga Infectious Disease Institute, Kampala, Uganda

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Genome Evolution of Kaposi Sarcoma-Associated Herpesvirus (KSHV) in PLWH" by Dirk P. Dittmer University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Themed Discussion: KS and KSHV: New Developments in Diagnosis, Therapy, and Pathogenesis

"Discussion with Audience Q&A" by

Themed Discussion: Meeting the Treatment and Prevention Needs of Transgender Women

"Session Overview" by Tonia Poteat Duke University, Durham, NC, USA

Themed Discussion: Meeting the Treatment and Prevention Needs of Transgender Women

"Recent HIV Acquisition Among Transgender Women From Midwest Brazil" by Sylvia L. M. Teixeira Oswaldo Cruz Institute – Fiocruz, Rio de Janeiro, Brazil

Themed Discussion: Meeting the Treatment and Prevention Needs of Transgender Women

"High HIV Burden Among Transgender Women in the State Capital and Rural Towns in Central Brazil" by Bruno Vinícius D. Diniz e Silva Federal University of Goias, Goiânia, Brazil

Themed Discussion: Meeting the Treatment and Prevention Needs of Transgender Women

"Time to Antiretroviral Initiation Among Transgender Women Living With HIV in France (1997-2022)" by Juliette Hemery French National Institute of Health and Medical Research (Inserm), Paris, France

Themed Discussion: Meeting the Treatment and Prevention Needs of Transgender Women

"Discussion with Audience Q&A" by

Science Spotlight: Advances in Sexual and Reproductive Health in HIV

"Incidence of Intended & Unintended Pregnancies Among Women With HIV on ART: 5-Year Cohort in Abidjan" by Prescilia Visi Vumba University of Bordeaux, Bordeaux, France

Science Spotlight: Advances in Sexual and Reproductive Health in HIV

"PrEP Eligible but Missed: Preliminary Evidence Unlocking the Potential of Family Planning Services" by Brenice Duroseau The Johns Hopkins University, Baltimore, MD, USA

Science Spotlight: Advances in Sexual and Reproductive Health in HIV

"STAR: A Prospective Cohort of Women of Reproductive Age With and Without HIV in the Southern US" by Elizabeth F. Topper The Johns Hopkins University, Baltimore, MD, USA

Science Spotlight: ART-Related and Social Determinants of TB Transmission and Treatment Outcomes

"Neuropsychiatric Outcomes in Adults With HIV and TB on Twice-Daily BIC/FTC/TAF With Rifampicin" by Gillian L. Dorse Centre for the AIDS Programme of Research in South Africa, Durban, South Africa

Science Spotlight: Biomarkers for NeuroHIV Informing Pathogenesis

"Plasma CNS Tissue Markers in Heavily Treatment-Experienced PWH in the PRESTIGIO Registry" by Andrea Calcagno University of Turin, Turin, Italy

Science Spotlight: Biomarkers for NeuroHIV Informing Pathogenesis

"Higher suPAR Relates to Domain-Specific Cognitive Function in Virally Suppressed Women With HIV" by Hemil Gonzalez Rush University Medical Center, Chicago, IL, USA

Science Spotlight: Biomarkers of Aging

"Epigenetic Age Acceleration and CD4/CD8 Ratio in People With Well-Controlled HIV Infection" by Alejandro de Gea Grela Hospital La Paz Institute for Health Research, Madrid, Spain

Science Spotlight: Biomarkers of Aging

"Validation of SARC-F Tool for Sarcopenia Screening in People Aging With HIV" by Joselito Malca Hernandez Yale University, New Haven, CT, USA

Science Spotlight: CD8 T Cells in Infection and After Vaccination

"TCR Convergence in HIV Controllers: Insights Into Natural Viral Suppression" by Alexandra Vujkovic Institute of Tropical Medicine, Antwerp, Belgium

Science Spotlight: CD8 T Cells in Infection and After Vaccination

"HIV-Infection Does Not Generally Confer Higher Resistance to CTL-Mediated Lysis" by Niklas Bachmann The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Science Spotlight: CD8 T Cells in Infection and After Vaccination

"HIV-Specific T & Humoral Response: Data From the First Pediatric Combined Therapeutic Vaccine Trial" by Arianna Rotili University of Rome Tor Vergata, Rome, Italy

Science Spotlight: Choice and Options as Prevention Tools

"Patterns of Choice, Switching, and Discontinuation of Oral and Injectable PrEP Among Adolescents" by Laio Magno Santos de Sousa Federal University of Bahia, Salvador, Brazil

Science Spotlight: Complications in Maternal HIV

"Prior Pregnancy Affects Aging-Related Non-AIDS Comorbidity Burden in US Women With and Without HIV" by Lauren F. Collins Emory University, Atlanta, GA, USA

Science Spotlight: Criminal Justice, Mental Health, and Syndemics Intersect With HIV

"A Syndemic View of Criminal Justice: Jail’s Impact on HIV, Syphilis, and Overdose in Washington 2023" by Steven J. Erly Washington State Department of Health, Olympia, WA, USA

Science Spotlight: Criminal Justice, Mental Health, and Syndemics Intersect With HIV

"HIV Acquisition After Prison Release in Washington State and Implications for Prevention Efforts" by Danika A. Troupe Washington State Department of Health, Olympia, WA, USA

Science Spotlight: Epidemiology of HIV in Transgender and Nonbinary Persons

"Recent HIV Acquisition Among Transgender Women From Midwest Brazil" by Sylvia L. M. Teixeira Oswaldo Cruz Institute – Fiocruz, Rio de Janeiro, Brazil

Science Spotlight: Health and Outcomes of Children Exposed to HIV/ART in Utero

"Insulin-Like Growth Factors and Stunting in African Infants Exposed to HIV and Uninfected" by Brenda C. Kakayi Makerere University–Johns Hopkins University Research Collaboration, Kampala, Uganda

Science Spotlight: Host-HIV Interaction

"Untangling the Impact of CD101 on HIV-1 Transmission" by Phuong Vo University of Washington, Seattle, WA, USA

Science Spotlight: Host-HIV Interaction

"Tuberculosis Promotes the Persistence of Genetically-Intact HIV in People With HIV and Tuberculosis" by Samantha K. Cronin The University of Sydney, Sydney, Australia

Science Spotlight: Kaposi Sarcoma: Diagnosis, Treatment, Pathogenesis, and KSHV

"Neuropilin-1 Is Required for KSHV Lytic Replication in Primary Effusion Lymphoma" by Anna Serquina National Cancer Institute, Bethesda, MD, USA

Science Spotlight: Mental Health

"Depression and Suicide Risk Among Sexual and Gender Minorities: Insights From the ImPrEP CAB Brasil" by David Richer Araujo Coelho Massachusetts General Hospital, Boston, MA, USA

Science Spotlight: Modeling

"Estimated Benefits of Providing On-Demand PrEP Options for Women in Cape Town: A Modeling Study" by Dobromir Dimitrov Fred Hutchinson Cancer Center, Seattle, WA, USA

Science Spotlight: Neuroimaging in HIV

"Analyzing Neuroanatomical Heterogeneity in HIV-Associated Cognitive Impairment" by Audrey Chun Washington University in St Louis, St Louis, MO, USA

Science Spotlight: Non-HIV Viruses

"Monocyte Dysregulation in PASC With Ongoing Pulmonary Symptoms" by Thomas K. Awamura University of Hawaii at Manoa, Honolulu, HI, USA

Science Spotlight: Novel Interventions Toward an HIV Cure

"HIV Remission After Allogeneic Hematopoietic Stem Cell Transplant From CCR5Δ32/Δ32 Sibling Donor" by Marius Trøseid Oslo University Hospital, Oslo, Norway

Science Spotlight: Renal Disease

"APOL1 Genotype and Graft Function in South African HIV+-to-HIV+ Kidney Transplant Recipients" by Robert Freercks Nelson Mandela University, Gqeberha, South Africa

Science Spotlight: Self, Couple, and Mobile Testing

"Evaluating the Effectiveness and Population Impact of Status-Neutral HIV Screening in AZ" by Lazaro Ruiz University of Arizona, Tucson, AZ, USA

Science Spotlight: Steatotic Liver Disease

"Liver Steatosis Progression With Integrase Inhibitors in HIV Adults in Low-/Middle-Income Countries" by Marie Kerbie Plaisy University of Bordeaux, Bordeaux, France

Science Spotlight: Still Here: Syphilis

"Epidemic of Treponema pallidum Strains in Japan and Biomarkers for Molecular Epidemiology" by Eisuke Adachi University of Tokyo Institute of Medical Science, Tokyo, Japan

Science Spotlight: Strategies for an HIV Cure

"Temsavir Treatment Improves Recognition of HIV-1 Infected Cells by Broadly Neutralizing Antibodies" by Hangfei Qi ViiV Healthcare, Durham, NC, USA

Science Spotlight: The Intersection of HIV With COVID-19

"Disparities in COVID-19 Therapeutics Access Among People With and Without HIV: An N3C Analysis" by Emmanuel Nazaire Essam Nkodo University of Nebraska Medical Center, Omaha, NE, USA

Science Spotlight: The Intersection of HIV With COVID-19

"Impact of COVID-19 Pandemic in Deaths of PLWH From ART Program of a Peruvian Hospital" by Jorge Tello Arana Universidad Científica del Sur, Lima, Peru

Symposium: Closing the Gaps in the HIV Response

"Session Overview" by Thiago Torres Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil

Symposium: Closing the Gaps in the HIV Response

"Immediate Challenges and Long-Term Goals of the HIV Response" by Jeffrey Imai-Eaton Harvard TH Chan School of Public Health

Symposium: Closing the Gaps in the HIV Response

"Integration and Sustainability of the Global HIV Response" by Tsitsi Apollo Zimbabwe Ministry of Health and Child Care, Harare, Zimbabwe

Symposium: Closing the Gaps in the HIV Response

"Innovations in HIV Service Delivery: Building a Path Forward with Those Left Behind" by Izukanji Sikazwe Centre for Infectious Disease Research in Zambia, Lusaka, Zambia

Symposium: Closing the Gaps in the HIV Response

"Discussion with Audience Questions and Answers" by

Symposium: Deciphering the Mystery of Viral Rebound

"Utilizing a Barcoded Virus Model to Identify the Source of Viral Rebound" by Brandon Keele Frederick National Laboratory for Cancer Research, Frederick, MD, USA

Symposium: Deciphering the Mystery of Viral Rebound

"Cellular and Tissue Sources of Viral Persistence and Rebound" by Linos Vandekerckhove HIV Cure Research Center, Ghent University, Ghent, Belgium

Symposium: Deciphering the Mystery of Viral Rebound

"Immune Responses During Viral Rebound" by Rachel Rutishauser University of California San Francisco, San Francisco, CA, USA

Symposium: Deciphering the Mystery of Viral Rebound

"Discussion with Audience Questions and Answers" by

Symposium: Filling the Gaps: Challenges and Opportunities in the Care of Children and Youth With Perinatal HIV

"Advanced HIV Disease in Children" by Pablo Rojo Hospital Universitario 12 de Octubre, Madrid, Spain

Symposium: Filling the Gaps: Challenges and Opportunities in the Care of Children and Youth With Perinatal HIV

"HIV Care Continuum in Children" by Irene Njuguna University of Washington, Seattle, WA, USA

Symposium: Filling the Gaps: Challenges and Opportunities in the Care of Children and Youth With Perinatal HIV

"Sexual, Reproductive, and Pregnancy Health Among People With Perinatal HIV" by Caroline Foster Imperial College Healthcare NHS Trust, London, UK

Symposium: Filling the Gaps: Challenges and Opportunities in the Care of Children and Youth With Perinatal HIV

"Discussion with Audience Questions and Answers" by

Tuesday Plenary Session

"CROI Program Committee Chair Welcome to Tuesday" by Wafaa M. El-Sadr ICAP at Columbia University, New York, NY, USA

Tuesday Plenary Session

"HIV Acquisition and Prevention During Pregnancy and Postpartum" by John Kinuthia Kenyatta National Hospital, Nairobi, Kenya

Tuesday Plenary Session

"Systems Vaccinology" by Bali Pulendran Stanford University, Stanford, CA, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Introduction of Speakers Part 1" by

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Efficacy and Safety of Lenacapavir, Teropavimab, and Zinlirvimab: Phase II Week 26 Primary Outcome" by Onyema Ogbuagu Yale University, New Haven, CT, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Proof-of-Concept Trial of VH4524184 (VH-184), a Third-Generation Integrase Strand Transfer Inhibitor" by Luise Rogg ViiV Healthcare, Durham, NC, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Proof-of-Concept Trial of Oral VH4011499 (VH-499), a New HIV-1 Capsid Inhibitor" by Paul Benn ViiV Healthcare, Brentford, UK

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Pharmacokinetics and Safety of Once-Yearly Formulations of Lenacapavir" by Renu Singh Gilead Sciences, Inc, Foster City, CA, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Questions and Answers Part 1" by

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Introduction of Speakers Part 2" by

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Elucidating the Mechanism by Which Nucleocapsid Mutations Confer Resistance to InSTIs" by Yuta Hikichi National Cancer Institute at Frederick, Frederick, MD, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Selection of Nucleocapsid Mutations With Virologic Failure of Tenofovir/Lamivudine/Dolutegravir" by Kerri J. Penrose University of Pittsburgh, Pittsburgh, PA, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Optimizing On-Demand Tenofovir Disoproxil Fumarate/Emtricitabine Dosing in Women for HIV Prevention" by Mackenzie Cottrell University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Safety and Antiviral Efficacy of a Broad-Spectrum siRNA SNS812 Targeting SARS-CoV-2: Phase II Trial" by Shey-Ying Chen National Taiwan University Hospital, Taipei, Taiwan

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Host and Disease Factors Were Not Associated With Mpox Resolution in Participants Receiving Tpoxx" by William A. Fischer II University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Oral Abstract: Antivirals For HIV, MPXV, and SARS-CoV-2: New Drug Strategies and Resistance

"Questions and Answers Part 2" by

Oral Abstract: Immunology and Vaccines

"Introduction of Speakers Part 1" by

Oral Abstract: Immunology and Vaccines

"Profiling Therapeutic Vaccine-Driven HIV-Specific CD8 T Cells With Single-Cell TCR Sequencing Assays" by Rafael Tiburcio University of California San Francisco, San Francisco, CA, USA

Oral Abstract: Immunology and Vaccines

"Efficacy of Bivalent Versus Monovalent COVID-19 Vaccines Among People With HIV, Ubuntu Trial, 2022-24" by Sufia Dadabhai The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

Oral Abstract: Immunology and Vaccines

"T-Cell Responses Induced by GS-1966+GS-1144 Vaccines in Virally Suppressed People With HIV" by Devi Sengupta Gilead Sciences, Inc, Foster City, CA, USA

Oral Abstract: Immunology and Vaccines

"Lymph Node HIV-Specific CD8 T Cells of HIV Controllers Harbour a Specific Transcriptomic Signature" by Andrea Mastrangelo Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Oral Abstract: Immunology and Vaccines

"Questions and Answers Part 1" by

Oral Abstract: Immunology and Vaccines

"Introduction of Speakers Part 2" by

Oral Abstract: Immunology and Vaccines

"HIV-Specific CD8+ T Cell Stemness Predicts Postintervention Control of Viremia" by David R. Collins Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA

Oral Abstract: Immunology and Vaccines

"Immunologic Impact of Short-Term BCL2 Inhibition at ART Initiation on SIV-Infected Rhesus Macaques" by Tomas Raul Wiche Salinas Emory University, Atlanta, GA, USA

Oral Abstract: Immunology and Vaccines

"Bispecific Antibody VRC07/PGT121 Protects Against High-Dose Intravenous SHIV-BG505 Challenge" by Matthew S. Parsons Armed Forces Research Institute of Medical Sciences in Bangkok, Bangkok, Thailand

Oral Abstract: Immunology and Vaccines

"Time-to-Rebound Measurements in ATI Trials With bNAb Intervention Are Confounded by Autologous NAbs" by Mauro Garcia The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Oral Abstract: Immunology and Vaccines

"Broad V2-Apex bNAb Activity in HIV-1 Through a Novel, K169-Independent bNAb" by Maria C. Hesselman University of Zurich, Zurich, Switzerland

Oral Abstract: Immunology and Vaccines

"Questions and Answers Part 2" by

Oral Abstract: New Frontiers in STI Prevention

"Introduction of Speakers Part 1" by

Oral Abstract: New Frontiers in STI Prevention

"Missed Opportunities for Syphilis Diagnosis With Targeted Compared to Universal Screening" by Kimberly A. Stanford University of Chicago Medical Center, Chicago, IL, USA

Oral Abstract: New Frontiers in STI Prevention

"Higher Odds of Congenital Syphilis With 9- vs 7-Day Prenatal Treatment Intervals for Late Syphilis" by Kelly A. Johnson University of California San Francisco, San Francisco, CA, USA

Oral Abstract: New Frontiers in STI Prevention

"DoxyPEP Eligibility, Use, and Potential for STI Reduction in a Large HIV Cohort in Washington, DC" by Amanda D. Castel The George Washington University, Washington, DC, USA

Oral Abstract: New Frontiers in STI Prevention

"High Sustained Effectiveness of Doxycycline PEP for STI Prevention After Clinical Implementation" by Hyman Scott San Francisco Department of Public Health, San Francisco, CA, USA

Oral Abstract: New Frontiers in STI Prevention

"Questions and Answers Part 1" by

Oral Abstract: New Frontiers in STI Prevention

"Introduction of Speakers Part 2" by

Oral Abstract: New Frontiers in STI Prevention

"The Doxy-PEP Continuum Among Patients Receiving Care at a Sexual Health Clinic in San Francisco" by Michael P. Barry San Francisco AIDS Foundation, San Francisco, CA, USA

Oral Abstract: New Frontiers in STI Prevention

"Global Modelling Analysis: Impact of Improved HPV Vaccination on Noncervical Cancers in PLWHIV" by Namwa Wongkalasin Imperial College London, London, UK

Oral Abstract: New Frontiers in STI Prevention

"Impact of Urine TFV Testing on PrEP Adherence in South African Pregnant and Postpartum Women: An RCT" by Dvora L. Joseph Davey University of California Los Angeles, Los Angeles, CA, USA

Oral Abstract: New Frontiers in STI Prevention

"Questions and Answers Part 2" by

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Introduction of Speakers Part 1" by

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Replication-Competent HIV-Infected Cells Have Deoxyuracil-Containing Proviruses" by Rodrigo Matus Nicodemos Vaccine Research Center, Bethesda, MD, USA

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Gag-Mediated Control Over CARD8 Activation During HIV-1 Assembly" by Ivy K. Hughes Boston University, Boston, MA, USA

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Direct Visualization of HIV-1 Nuclear Import and Its Interplay With the Nuclear Pore" by Yao Shen University of Oxford, Oxford, UK

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Visualizing the Cell Biology of HIV Latency and Reactivation" by Jonathan Karn Case Western Reserve University, Cleveland, OH, USA

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Questions and Answers Part 1" by

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Introduction of Speakers Part 2" by

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Single-Cell Spatial Profiling Identified Intact HIV+ Cells in Lymph Nodes" by Amare Eshetu Yale University, New Haven, CT, USA

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Lenacapavir Directs Specific Proteasome-Mediated Degradation of Gag Proteins in HIV-Infected Cells" by Clayton Faua University Hospital of Strasbourg, Strasbourg, France

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"RhCMV Expands CCR5 Memory CD4 T Cells and Increases Acute-Phase Seeding of SIV DNA in the Gut Mucosa" by Chrysostomos Perdios Tulane National Primate Research Center, Covington, LA, USA

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Differential Replication, Innate Immune Control, and Virulence of Global and Endemic Clade II MPXV" by Rebecca P. Sumner University Surrey, Guildford, UK

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Nef Modulates Actin to Prevent Postintegration Sensing of HIV-1" by Alexandre Laliberté Ulm University Medical Center, Ulm, Germany

Oral Abstract: What Do Viruses Do, and How Do They Do It?

"Questions and Answers Part 2" by

Themed Discussion: Machine Learning: Gearing Up for the Future

"Scientific Overview of Machine Learning: Gearing Up for the Future" by Julia Marcus Harvard Pilgrim Health Care Institute, Boston, MA, USA

Themed Discussion: Machine Learning: Gearing Up for the Future

"Machine Learning to Predict Persons With HIV at Risk of Falling Out of Care" by Thomas Martin University of California San Diego, La Jolla, CA, USA

Themed Discussion: Machine Learning: Gearing Up for the Future

"Enhanced Language Models for Predicting and Understanding HIV Care Disengagement" by Waverly Wei University of Southern California, Los Angeles, CA, USA

Themed Discussion: Machine Learning: Gearing Up for the Future

"An AI-Powered Preventive Intervention for Stigma and Suicidal Ideation in HIV Self-Management" by Diego S. Villanueva Guzman Research Institute of McGill University Health Centre, Montreal, Canada

Themed Discussion: Machine Learning: Gearing Up for the Future

"Discussion with Audience Q&A" by

Themed Discussion: Natural-Born Killers

"Session Overview" by Galit Alter Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA

Themed Discussion: Natural-Born Killers

"HLA-E Prevents Natural Killer Cell Inhibition of HIV-1 Replication in Peripheral Blood CD4+ T Cells" by Amanda M. Dudek Stanford University, Stanford, CA, USA

Themed Discussion: Natural-Born Killers

"Differential CD8T/NK Cell-Mediated HIV-1 Control After TIGIT or KLRG1 Blockade and ART in hBLT Mice" by Ildefonso Sánchez-Cerrillo Hospital Universitario de La Princesa, Madrid, Spain

Themed Discussion: Natural-Born Killers

"Elucidating the Role of Natural Killer Cells in Antibody Breadth During HIV Infection" by Izumi de los Rios Kobara Stanford University, Stanford, CA, USA

Themed Discussion: Natural-Born Killers

"NF-kappa-B Signaling in Natural Killer Cells Predicts Post-Treatment HIV Control" by Ashley F. George Gladstone Institutes, San Francisco, CA, USA

Themed Discussion: Natural-Born Killers

"RV550: IL-15 Superagonist N-803 With ART in Acute HIV Infection Enhances T and NK Cell Proliferation" by Hiroshi Takata Oregon Health and Science University, Portland, OR, USA

Themed Discussion: Natural-Born Killers

"Discussion with Audience Q&A" by

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"Session Overview" by Alex Sigal Africa Health Research Institute, Mtubatuba, South Africa

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"SARS-CoV-2 Intra-Host Evolution During Acute Infection in People With COVID-19" by Agostino Riva University of Milan, Milan, Italy

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"Evolving of Immune Evasion During a SARS-CoV-2 Chronic Infection: A Pathway to Variants of Concern" by Rui Galao King's College London, London, UK

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"Genetic Mutation Differences Patterns of SARS-CoV-2 in Immunocompromised Patients Versus Controls" by Karen Zafilaza Assistance Publique – Hôpitaux de Paris, Paris, France

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"ScRNA-seq of HRSV/SARS-CoV-2 Co-Infection Reveals Unique Cellular Responses and lncRNA Signatures" by Claudia Vanetti University of Milan, Milan, Italy

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"Prevalence, Spread, and Mutation of SARS-CoV-2 Variants in COVID-19 Testing in Salvador, Brazil" by Anna Carolina Dantas Federal University of Bahia, Salvador, Brazil

Themed Discussion: SARS-CoV-2 Persistence and Evolutions

"Discussion with Audience Q&A" by

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"Session Overview" by Salome Charalambous The Aurum Institute, Johannesburg, South Africa

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"Evaluating the Accuracy of Standard F TB-Feron FIA for TB Infection Diagnosis in Vietnam" by Han Thi Nguyen Karolinska Institute, Stockholm, Sweden

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"Effect of Tuberculosis Preventive Therapy on Mtb-Specific T-Cell Profile in the A5279/BRIEF TB Trial" by Pablo C. Alarcon University of Cincinnati Medical Center, Cincinnati, OH, USA

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"The Impact of Rifampin Drug Interactions on TPT Completion and Safety Using High-Dose vs Standard" by Jinell White Alberta Health Services, Calgary, Canada

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"Patient and Provider Preferences for Long-Acting Tuberculosis Preventive Therapy" by Marcia C. Vermeulen University of Cape Town, Cape Town, South Africa

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"Weekly Rifapentine and Isoniazid (3HP) vs Isoniazid Preventive Therapy (6H) Among People With HIV" by Dickens Onyango Kisumu County Department of Medical Services, Public Health, and Sanitation, Kisumu, Kenya

Themed Discussion: TB Infection and Prevention: Testing, Treatment, and Strategies

"Discussion with Audience Q&A" by

Science Spotlight: Advanced HIV

"C-Reactive Protein as a Predictor of Hospitalization and Mortality in Advanced HIV Disease in Uganda" by Elizabeth L. Schwartz University of Minnesota, Minneapolis, MN, USA

Science Spotlight: Antiretrovirals and Birth Outcomes

"Perinatal and Infant Outcomes After Bictegravir Exposure in Pregnancy: A Canadian Surveillance Study" by Jeffrey Man Hay Wong University of British Columbia, Vancouver, Canada

Science Spotlight: Barriers to Uptake and Persistence With Biomedical Prevention

"Impact of Initiation Delay, Duration, and Prior PrEP Usage on FTC/TDF-Containing PEP Efficacy" by Lanxin Zhang Robert Koch Institute, Berlin, Germany

Science Spotlight: Drug-Drug Interactions and Pharmacology Challenges With Important Coconditions

"Pharmacokinetics of Twice-Daily TAF in Adults With HIV-Associated TB on BIC/FTC/TAF and Rifampicin" by Emmanuella C. Osuala Centre for the AIDS Programme of Research in South Africa, Durban, South Africa

Science Spotlight: Drug-Drug Interactions and Pharmacology Challenges With Important Coconditions

"Reduced Metformin Concentrations in Obese Women With HIV Treated With Dolutegravir" by Roland van Rensburg Stellenbosch University, Cape Town, South Africa

Science Spotlight: Frailty and Aging

"Falls Associated With High Medication Regimen Complexity in People With HIV" by Yunhan Chen Boston Medical Center, Boston, MA, USA

Science Spotlight: Global STI Epidemiology

"Sexually Transmitted Infection Prevalence Among Adolescents and Adults in Western Kenya" by Julius L. Tonzel US Military HIV Research Program, Bethesda, MD, USA

Science Spotlight: HBV Diagnostics and Treatment

"HBV Seroconversion in People With HIV: Relevance of Clinical History and Viral Markers Monitoring" by Marianna Menozzi AOU Policlinico di Modena, Modena, Italy

Science Spotlight: HIV-Related Cancer: Epidemiology, Incidence, Demographics

"Predictors of Mortality Among Patients With Virus-Associated Cancers in a High HIV-Prevalence Region" by Dorothy Mangale Washington University, St Louis, MO, USA

Science Spotlight: Immune Pressure on HIV Reservoirs

"Autologous IgGs Mediate Log Reductions in HIV Infection in a PTC, Contributing to ART-Free Remission" by Junlin Zhuo The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Science Spotlight: Immune Pressure on HIV Reservoirs

"Afucosylation of Broadly Neutralising Antibodies to Eliminate HIV+ CD4+ T Cells and Macrophages" by Morgane Brunton-O'Sullivan Burnet Institute, Melbourne, Australia

Science Spotlight: Immune Pressure on HIV Reservoirs

"Engineering Natural Killer Cells With NKp30-Based Chimeric Antigen Receptors (CARs) to Target HIV" by Ruoxi Pi Stanford University, Stanford, CA, USA

Science Spotlight: Immune Pressure on HIV Reservoirs

"Preclinical Evaluation of Effector Function-Enhanced Variants of N6 bNAb" by David Wensel ViiV Healthcare, Branford, CT, USA

Science Spotlight: Improving HIV Testing in Clinical Settings

"Missed Opportunities: HIV Screening Deficits in Japanese Syphilis Patients" by Toshibumi Taniguchi Chiba University, Chiba, Japan

Science Spotlight: Improving HIV Testing in Clinical Settings

"Machine Learning Risk Stratification Compared With a Counselor-Guided Screening Tool" by Daniel G. Wandina Gold Star Kenya, Karuri, Kenya

Science Spotlight: Incident HIV Infection

"Contact Investigation of Incident HIV in a Population Cohort: Implications for Case Finding and PrEP" by Robert Ssekubugu Rakai Health Sciences Program, Kalisizo, Uganda

Science Spotlight: Incident HIV Infection

"New HIV-1 Diagnoses Among Different Generations of MSM in the Netherlands: Focus on Gen-Z" by Annemarie M. J. Wensing University Medical Center Utrecht, Utrecht, Netherlands

Science Spotlight: Long-Acting Therapy: What Observational Data Tell Us About the "Real World"

"Long-Term CAB+RPV LA Effectiveness in Virologically Suppressed Individuals in the OPERA Cohort" by Michael Sension CAN Community Health, Fort Lauderdale, FL, USA

Science Spotlight: Long-Acting Therapy: What Observational Data Tell Us About the "Real World"

"Clinical Outcomes Among Virologically Suppressed Women Receiving CAB+RPV LA in the OPERA Cohort" by Jessica A. Altamirano CAN Community Health, Fort Lauderdale, FL, USA

Science Spotlight: Long-Acting Therapy: What Observational Data Tell Us About the "Real World"

"Long-Acting Cabotegravir and Rilpivirine in Older People With HIV in the GEPPO Cohort" by Andrea Calcagno University of Turin, Turin, Italy

Science Spotlight: Long-Acting Therapy: What Observational Data Tell Us About the "Real World"

"Long-Acting Cabotegravir/Rilpivirine in Real Life: Sex-Based Characteristics, PROs, and Effectiveness" by Ana González-Cordón Hospital Clinic of Barcelona, Barcelona, Spain

Science Spotlight: Managing Maternal HIV

"HIV Drug Resistance Patterns Among Pregnant Women After Dolutegravir Scale-Up in Sub-Saharan Africa" by Linda Stoeger Barcelona Institute for Global Health, Barcelona, Spain

Science Spotlight: New Agents and Novel Administration

"Evaluating Efficacy of Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide Administered via Tube" by Joshua T. Mercure Massachusetts General Hospital, Boston, MA, USA

Science Spotlight: Novel Interventions

"nPEP When You Need It: A 24/7 Post-Exposure Prophylaxis Hotline in the District of Columbia" by Rachel Harold District of Columbia Department of Health, Washington, DC, USA

Science Spotlight: PASC: Immunobiologic, Metabolic, and Cardiovascular Complications

"Hormonal Dysregulation in Long COVID: Exploring the Salivary Cortisol Profile" by Marta Camici IRCCS Lazzaro Spallanzani, Rome, Italy

Science Spotlight: PASC: Immunobiologic, Metabolic, and Cardiovascular Complications

"Age-Dichotomous Associations of Long COVID With Frequency of Public SARS-CoV-2 Memory TCRs" by Selin Akbas The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Science Spotlight: Persistence and Evolution of SARS-CoV-2

"ScRNA-seq of HRSV/SARS-CoV-2 Co-Infection Reveals Unique Cellular Responses and lncRNA Signatures" by Claudia Vanetti University of Milan, Milan, Italy

Science Spotlight: Persistence and Evolution of SARS-CoV-2

"Prevalence, Spread, and Mutation of SARS-CoV-2 Variants in COVID-19 Testing in Salvador, Brazil" by Anna Carolina Dantas Federal University of Bahia, Salvador, Brazil

Science Spotlight: PrEP Implementation: Hopes, Dreams, and Aspirations

"PURPOSE 1: Preference for Twice-Yearly Injection vs Daily Oral Pills for HIV PrEP in Cisgender Women" by Leila E. Mansoor Centre for the AIDS Programme of Research in South Africa, Durban, South Africa

Science Spotlight: Sexual Partner, Sexual Risk

"Vaginal and Anal Intercourse With Women Reported by Men Who Have Sex With Men, 2015-2019" by Karen W. Hoover Centers for Disease Control and Prevention, Atlanta, GA, USA

Science Spotlight: TB Preventive Therapy: Testing, Treatment Strategies, and Outcomes

"Patient and Provider Preferences for Long-Acting Tuberculosis Preventive Therapy" by Marcia C. Vermeulen University of Cape Town, Cape Town, South Africa

Science Spotlight: The HIV Care and Prevention Cascades: Novel Insights

"Refining Clinical Retention Metrics to Reflect the Realities of HIV Care in North America" by Peter F. Rebeiro Vanderbilt University Medical Center, Nashville, TN, USA

Science Spotlight: The HIV Care and Prevention Cascades: Novel Insights

"Neighborhood Resources and ARV Adherence Among Partnered US GBMSM: Mediation by Social Determinants" by Loren Dobkin University of Michigan, Ann Arbor, MI, USA

Science Spotlight: Treatment Continuity

"Detection and Linkage of PLWH Who Are Out of Care in 94 Emergency Departments Across the US" by Jamie L. Mignano Gilead Sciences, Inc, Foster City, CA, USA

Science Spotlight: Treatment Continuity

"Point-of-Care Urine Self-Testing Feasibility to Measure TFV Adherence and Predict Viral Suppression" by Renata Buccheri Vitalant Research Institute, San Francisco, CA, USA

Science Spotlight: Using Vaccines for Therapy

"Therapeutic HIV Vaccine ± TLR4 Adjuvant Impact on Monocyte Subsets in Early-Treated Youths With HIV" by Alessia Neri University of Rome Tor Vergata, Rome, Italy

Science Spotlight: Weight Gain

"Re-Examining InSTI Effects on Weight Gain Among Treatment-Naive People With HIV in North America" by Kassem Bourgi Nashville CARES, Nashville, TN, USA

Symposium: Breaking In and Setting Up Home: From HIV Nuclear Entry and Integration to Viral Gene Expression and Establishing the Reservoir

"How HIV Capsid Breaches the Nuclear Envelope Through Karyopherin Mimicry" by David Jacques University of New South Wales, Sydney, Australia

Symposium: Breaking In and Setting Up Home: From HIV Nuclear Entry and Integration to Viral Gene Expression and Establishing the Reservoir

"How HIV Integrates Into the Genome" by Alan N Engelman Dana–Farber Cancer Institute, Boston, MA, USA

Symposium: Breaking In and Setting Up Home: From HIV Nuclear Entry and Integration to Viral Gene Expression and Establishing the Reservoir

"Transcriptional and Epigenetic Regulation of HIV-1 Gene Expression" by Melanie Ott Gladstone Institutes, San Francisco, CA, USA

Symposium: Breaking In and Setting Up Home: From HIV Nuclear Entry and Integration to Viral Gene Expression and Establishing the Reservoir

"The Landscape of Proviral Integration in the HIV-1 Reservoir and Its Relationship to Latency and Reactivation" by Mary Kearney National Cancer Institute at Frederick, Frederick, MD, USA

Symposium: Breaking In and Setting Up Home: From HIV Nuclear Entry and Integration to Viral Gene Expression and Establishing the Reservoir

"Discussion with Audience Questions and Answers" by

Symposium: Hot Topic: Menopause and HIV

"Beyond Hot Flashes: Women's Lived Experience of Menopause" by Bridgette Picou The Well Project: Women's Research Initiative on HIV/AIDS, Brooklyn, NY, USA

Symposium: Hot Topic: Menopause and HIV

"Clinical Management of Women With HIV in Menopause" by Sara Looby Massachusetts General Hospital, Boston, MA, USA

Symposium: Hot Topic: Menopause and HIV

"Influence of Hormone Changes on Physiology, Virology, and Immunology" by Eileen Scully The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Symposium: Hot Topic: Menopause and HIV

"Discussion with Audience Questions and Answers" by

Symposium: Long-Acting Preexposure Prophylaxis for HIV Prevention

"Game Changed: Navigating the Era of Long-Acting Therapies for HIV Prevention" by Jonathan Li Brigham and Women's Hospital, Boston, MA, USA

Symposium: Long-Acting Preexposure Prophylaxis for HIV Prevention

"Complexities of HIV Diagnosis: What Lies Beneath" by Cheryl C. Johnson World Health Organization, Geneva, Switzerland

Symposium: Long-Acting Preexposure Prophylaxis for HIV Prevention

"Long-Acting Preexposure Prophylaxis: Why Can’t We Get to Scale?" by Cissy Kityo Joint Clinical Research Centre, Kampala, Uganda

Symposium: Long-Acting Preexposure Prophylaxis for HIV Prevention

"Discussion with Audience Questions and Answers" by

Symposium: Tuberculosis: The Long Game

"Long-Acting Treatments for Tuberculosis" by Eric Nuermberger The Johns Hopkins University, Baltimore, MD, USA

Symposium: Tuberculosis: The Long Game

"Post-Tuberculosis Disease: Opening Pandora's Box" by Brian Allwood Stellenbosch University, Cape Town, South Africa

Symposium: Tuberculosis: The Long Game

"Discussion with Audience Questions and Answers" by

Wednesday Plenary Session

"CROI Program Committee Chair Welcome to Wednesday" by Nicolas Chomont Université de Montréal, Montreal, Canada

Wednesday Plenary Session

"Long COVID: Causes, Consequences, and the Way Forward" by Roger Paredes IrsiCaixa, Badalona, Spain

Wednesday Plenary Session

"Weight Gain in People With HIV" by Jordan E. Lake University of Texas Health Science Center at Houston, Houston, TX, USA

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Introduction of Speakers Part 1" by

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Major Improvement in Age-Related Health Outcomes in People Living With HIV: An 18-Year Cohort Study" by Alejandro Garcia Hospital Ramón y Cajal, Madrid, Spain

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Early vs Deferred HIV Therapy and Cardiovascular Disease in People With HIV: The START Study" by Nila J. Dharan University of New South Wales Sydney, Sydney, Australia

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Epidemiology of Coronary Atherosclerosis Among People Living With HIV in Uganda" by Mark J. Siedner Massachusetts General Hospital, Boston, MA, USA

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Plaque, Inflammation, Subclinical Myocardial Injury, and MACE in the REPRIEVE Mechanistic Substudy" by Steven Grinspoon Massachusetts General Hospital, Boston, MA, USA

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Questions and Answers Part 1" by

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Introduction of Speakers Part 2" by

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Frailty Is Associated With Higher MACE Incidence but Does Not Appear to Modify Pitavastatin Effects" by Kristine M. Erlandson University of Colorado Anschutz Medical Campus, Aurora, CO, USA

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Prognostic Value of Epigenetic Age Acceleration in People With Well-Controlled HIV Infection" by Patricia Martínez-Martín La Paz University Hospital, Madrid, Spain

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Semaglutide Stabilizes Epigenetic Aging in People With HIV-Associated Lipohypertrophy" by Michael J. Corley Weill Cornell Medicine, New York, NY, USA

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Letermovir for CMV Suppression Improves Immunologic and Functional Aging Outcomes in Treated HIV" by Sara Gianella Weibel University of California San Diego, La Jolla, CA, USA

Oral Abstract: Cardiometabolic Complications and Aging: The Clock Is Ticking

"Questions and Answers Part 2" by

Oral Abstract: Expanding the Prevention Toolbox

"Introduction of Speakers Part 1" by

Oral Abstract: Expanding the Prevention Toolbox

"Long-Acting Cabotegravir PrEP Uptake and Persistence in a Large US Healthcare System" by Michael Traeger Harvard Pilgrim Health Care Institute, Boston, MA, USA

Oral Abstract: Expanding the Prevention Toolbox

"ImPrEP CAB Brasil: Enhancing PrEP Coverage With CAB-LA in Young Key Populations" by Beatriz Grinsztejn Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil

Oral Abstract: Expanding the Prevention Toolbox

"Estimation of Prevention-Effective CAB-LA Concentrations Among MSM/TGW in HPTN 083" by Brett S. Hanscom Fred Hutchinson Cancer Center, Seattle, WA, USA

Oral Abstract: Expanding the Prevention Toolbox

"Adherence to F/TAF in Cisgender Women Prevents HIV With Low Risk of Resistance or Diagnostic Delay" by Flavia M. Kiweewa Makerere University–Johns Hopkins University Research Collaboration, Kampala, Uganda

Oral Abstract: Expanding the Prevention Toolbox

"Questions and Answers Part 1" by

Oral Abstract: Expanding the Prevention Toolbox

"Introduction of Speakers Part 2" by

Oral Abstract: Expanding the Prevention Toolbox

"Performance of HIV RNA Screening in the Context of Long-Acting Injectable Cabotegravir in HPTN 084" by Sinead Delany-Moretlwe University of the Witwatersrand, Johannesburg, South Africa

Oral Abstract: Expanding the Prevention Toolbox

"PILLAR Month 12 Clinical Results: Zero HIV Acquisition and High Persistence With CAB LA for PrEP" by Taimur Khan Fenway Health, Boston, MA, USA

Oral Abstract: Expanding the Prevention Toolbox

"Response to HIV Treatment After Long-Acting Cabotegravir Preexposure Prophylaxis in HPTN 083" by Raphael J. Landovitz University of California Los Angeles, Los Angeles, CA, USA

Oral Abstract: Expanding the Prevention Toolbox

"An Injectable Multipurpose Implant With CAB and MPA for Long-Acting HIV Prevention and Contraception" by S. Rahima Benhabbour University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Oral Abstract: Expanding the Prevention Toolbox

"Questions and Answers Part 2" by

Oral Abstract: Gaps and Solutions in the HIV Response

"Introduction of Speakers Part 1" by

Oral Abstract: Gaps and Solutions in the HIV Response

"Preliminary Efficacy for HPTN 094: 26-Week RCT of Integrated Strategies for People Who Inject Drugs" by Steve Shoptaw University of California Los Angeles, Los Angeles, CA, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"Most With HIV Viremia Are Not in Care Despite High ART Coverage: A Population-Based Study in Uganda" by Silas Odiya Rakai Health Sciences Program, Kalisizo, Uganda

Oral Abstract: Gaps and Solutions in the HIV Response

"Low-Cost Counseling Achieves Positive Outcomes for Malawi Men Disengaged From Care: Randomized Trial" by Kathryn L. Dovel University of California Los Angeles, Los Angeles, CA, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"Clinic Switching and Elevated HIV Viral Load in 6 African Countries: A Population-Based Study" by Joseph G. Rosen Brown University, Providence, RI, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"Questions and Answers Part 1" by

Oral Abstract: Gaps and Solutions in the HIV Response

"Introduction of Speakers Part 2" by

Oral Abstract: Gaps and Solutions in the HIV Response

"How Do Repeated Financial Incentives Affect HIV Care-Seeking Behaviors Over Time?" by Solis Winters University of California Berkeley, Berkeley, CA, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"Effect of a Person-Centered Care Intervention on Reengagement After Care Interruptions in Zambia" by Aaloke Mody Washington University in St Louis, St Louis, MO, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"Systems Analysis and Improvement Approach to Optimize Hypertension Care for People Living With HIV" by Sarah Gimbel University of Washington, Seattle, WA, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"SEARCH Integrated HIV/Hypertension Community Health Worker-Led Intervention in Rural East Africa" by Matt Hickey University of California San Francisco, San Francisco, CA, USA

Oral Abstract: Gaps and Solutions in the HIV Response

"Questions and Answers Part 2" by

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Introduction of Speakers Part 1" by

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Brain Volume Normalization After 96 Weeks of ART Started During Acute HIV Infection" by Robert Paul University of Missouri St Louis, St Louis, MO, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Spinal Cord as a Distinct Site of HIV Persistence and Dispersal in the Brain" by Mattia Trunfio University of California San Diego, La Jolla, CA, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Longitudinal Persistence of HIV DNA in CSF Over 4 Years Despite Up to 20 Years of ART" by Joshua C. Cyktor University of Pittsburgh, Pittsburgh, PA, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Single-Nuclei Multiome Analysis of CSF Cells Reveals Dendritic Cell Dysregulation Despite ART" by Shelli Farhadian Yale University, New Haven, CT, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Questions and Answers Part 1" by

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Introduction of Speakers Part 2" by

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Plasma Phosphorylated Tau 217 and Cognitive Decline in Older Thai People With HIV" by Akarin Hiransuthikul Chulalongkorn University, Bangkok, Thailand

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Semaglutide Improves Cognitive Function in HIV, Effect Mediated by Decrease in Inflammation" by Ornina Atieh Case Western Reserve University, Cleveland, OH, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Brain Gray and White Matter Alterations in Cognitive Long COVID" by Lindsay S. McAlpine Yale University, New Haven, CT, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Structural Brain Volumes Decrease After SARS-CoV-2 Infection Among People With HIV" by Jacob Bolzenius University of Missouri St Louis, St Louis, MO, USA

Oral Abstract: Viruses Always On My Mind: Viral Neuropathogenesis From Acute HIV to SARS-CoV-2

"Questions and Answers Part 2" by

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"(Introduction of Speakers)" by

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"Ensitrelvir to Prevent COVID-19 in Households: SCORPIO-PEP Phase III Placebo-Controlled Trial Results" by Frederick G. Hayden University of Virginia, Charlottesville, VA, USA

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"Tecovirimat Is Safe but Not Efficacious in People With Clade II Mpox" by Timothy Wilkin University of California San Diego, La Jolla, CA, USA

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"Randomized Trial of Long-Acting Cabotegravir and Rilpivirine in Africa (CARES): Week 96 Results" by Cissy Kityo Joint Clinical Research Centre, Kampala, Uganda

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"VH3810109 (N6LS) Efficacy and Safety in Adults Who Are Virologically Suppressed: The EMBRACE Study" by Babafemi Taiwo ViiV Healthcare, Durham, NC, USA

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"Switch to DOR/ISL (100/0.25 mg) QD From BIC/FTC/TAF: A Blinded Phase III Study in Adults With HIV-1" by Amy E. Colson Community Resource Initiative, Boston, MA, USA

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"Switch to DOR/ISL (100/0.25 mg) QD From Oral ART: An Open-Label Phase III Study in Adults With HIV-1" by Chloe Orkin Queen Mary University of London, London, UK

Oral Abstract: Late-Breaking Antiviral Therapy: It Doesn’t Get Any Hotter Than This!

"Questions and Answers" by

Themed Discussion: "Growing Up" With HIV Exposure

"Session Overview" by Ceri Evans University of Liverpool, Liverpool, United Kingdom

Themed Discussion: "Growing Up" With HIV Exposure

"Growth Faltering Is Partially Ameliorated by Infant Gut Bifidobacterium in Children Exposed to HIV" by Nicole Tobin University of California Los Angeles, Los Angeles, CA, USA

Themed Discussion: "Growing Up" With HIV Exposure

"Insulin-Like Growth Factors and Stunting in African Infants Exposed to HIV and Uninfected" by Brenda C. Kakayi Makerere University–Johns Hopkins University Research Collaboration, Kampala, Uganda

Themed Discussion: "Growing Up" With HIV Exposure

"Cardiometabolic Outcomes in HEU vs HU Children in a SA Birth Cohort: Influence of Maternal Lipids" by Calli Dogon Brown University, Providence, RI, USA

Themed Discussion: "Growing Up" With HIV Exposure

"Obesity and Metabolic Comorbidities in Young Adults With Perinatal HIV Exposure Without Infection" by Nikhita Chahal Massachusetts General Hospital, Boston, MA, USA

Themed Discussion: "Growing Up" With HIV Exposure

"Discussion with Audience Q&A" by

Themed Discussion: Hide and Seek: HIV in Tissues

"Session Overview" by Zabrina L. Brumme Simon Fraser University, Burnaby, Canada

Themed Discussion: Hide and Seek: HIV in Tissues

"HIV Reservoir in Jejunum Exhibit Distinct Phenotypic Features and Evoke Innate Cell Redistribution" by Marta Calvet-Mirabent Gladstone Institute, San Francisco, CA, USA

Themed Discussion: Hide and Seek: HIV in Tissues

"Predominance of Non-T Follicular Helper Cell Subsets in the Lymph Node Viral Reservoir During ART" by Vincent H. Wu University of Pennsylvania, Philadelphia, PA, USA

Themed Discussion: Hide and Seek: HIV in Tissues

"HIV Transcriptional Regulation in the CNS of ART-Suppressed People With HIV" by Janna Jamal Eddine RMIT University, Melbourne, Australia

Themed Discussion: Hide and Seek: HIV in Tissues

"Association of CSF Viral Compartmentalization and Macrophage Tropism With Neurosymptomatic HIV" by Laura P. Kincer University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Themed Discussion: Hide and Seek: HIV in Tissues

"Discussion with Audience Q&A" by

Themed Discussion: Lessons in DoxyPEP Implementation

"Session Overview" by Jennifer E. Balkus Public Health–Seattle & King County, Seattle, WA, USA

Themed Discussion: Lessons in DoxyPEP Implementation

"Post-Exposure Prophylaxis With Doxycycline (Doxy PEP) in a Cohort of High-Risk MSM: The PRIDOX Study" by Cristina Gómez-Ayerbe Hospital Universitario Virgen de la Victoria, Málaga, Spain

Themed Discussion: Lessons in DoxyPEP Implementation

"The Actual Need for DoxyPEP Might Not Be as Large as Expected" by Roberto Rossotti ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

Themed Discussion: Lessons in DoxyPEP Implementation

"Antimicrobial Consumption Among Users of Doxycycline Post-Exposure Prophylaxis in Milan, Italy" by Angelo Roberto Raccagni San Raffaele Vita-Salute University, Milan, Italy

Themed Discussion: Lessons in DoxyPEP Implementation

"DoxyPrEP Impact on the Microbiome of Men Who Have Sex With Men and Transgender Women on HIV PrEP" by Troy Grennan BC Centre for Disease Control, Vancouver, Canada

Themed Discussion: Lessons in DoxyPEP Implementation

"Discussion with Audience Q&A" by

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Session Overview" by

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Long COVID Associates With Slow Viral Clearance and Viral Rebound During Acute SARS-CoV-2 Infection" by Annukka Antar The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Longitudinal Changes in Arterial Stiffness and Inflammation From Pre- to Post-COVID-19 Infection" by Jhony Baissary Case Western Reserve University, Cleveland, OH, USA

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Preserved Adrenal Function in People With Long COVID" by Elizabeth Pasetes The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Plasma Biomarkers in Children and Young People With Long COVID" by Jon Izquierdo-Pujol IrsiCaixa, Badalona, Spain

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Immune Profile of Children With Post-COVID-19 Cardiac Contractility Alterations: A Prospective Study" by Costanza Di Chiara University of Padova, Padova, Italy

Themed Discussion: Long COVID: Pathogenesis and Clinical Manifestations

"Discussion with Audience Q&A" by

Science Spotlight: Antiviral Therapy for SARS-CoV-2

"Tracking Key Remdesivir Resistance Mutations in SARS-CoV-2 Using GISAID Data (2020-2024)" by Toshibumi Taniguchi Chiba University, Chiba, Japan

Science Spotlight: Atherosclerosis and Vascular Disease

"PLHIV Exhibit a COVID-19 Independent Increase of Cardiovascular Mortality in Brazil, 2019-2023" by Rodrigo Moreira Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil

Science Spotlight: Challenging and Innovative HIV Testing

"Impact of Point-of-Care HIV-1 RNA Testing on Time to HIV Confirmation and ART Start in Buenos Aires" by Carina Cesar Fundación Huésped, Buenos Aires, Argentina

Science Spotlight: Challenging and Innovative HIV Testing

"Characteristics of First-Time HIV Self-Testers Using the Online HIV Service ‘Stand By You’" by Kantarida Sripanidkulchai Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Science Spotlight: Diabetes and Metabolic Dysfunction

"Obstructive Sleep Apnea and Prevalent Diabetes Mellitus in the Multicenter AIDS Cohort Study" by Wassim A. Bouhsane The Johns Hopkins University, Baltimore, MD, USA

Science Spotlight: Dolutegravir Resistance

"Plasma Dolutegravir Exposure as a Triaging Tool for HIV Drug Resistance Testing by ONT Sequencing" by Hendrik J. Coetser University of the Witwatersrand, Johannesburg, South Africa

Science Spotlight: Dolutegravir Resistance

"HIV Drug Resistance by Next-Generation Sequencing After Transition to TLD in Uganda and South Africa" by Suzanne McCluskey Massachusetts General Hospital, Boston, MA, USA

Science Spotlight: DoxyPEP Reflections

"The Actual Need for DoxyPEP Might Not Be as Large as Expected" by Roberto Rossotti ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

Science Spotlight: Emerging Perspectives on Perinatal HIV Transmission

"Vertical HIV Transmission: Substantial Reductions but Not Elimination With Universal ART" by Nisha Jacob University of Cape Town, Cape Town, South Africa

Science Spotlight: Health and Outcomes of Young People With HIV

"Changes in Suicidality, Depression, and Anxiety After Integrative Mental Health Care in Thai Youth" by Tavitiya Sudjaritruk Chiang Mai University, Chiang Mai, Thailand

Science Spotlight: Health and Outcomes of Young People With HIV

"Kidney Dysfunction in Young People Living With HIV on Dolutegravir-Based Regimens in Kampala, Uganda" by Esther M. Nasuuna Infectious Diseases Institute, Kampala, Uganda

Science Spotlight: Hepatitis Epidemiology and Immunology

"HIV/HCV Coinfection: Extracellular Vesicles Modulate NK Functionality in Relation to Liver Fibrosis" by Ariel A. Osegueda Instituto de Investigaciones Biomédicas en Retrovirus y SIDA, Buenos Aires, Argentina

Science Spotlight: HIV Acquisition and Prevention During Pregnancy and Breastfeeding

"Impact of Offering PrEP Choice on HIV Incidence in High-Risk Pregnant Women in Kenya" by Tessa Concepcion University of Washington, Seattle, WA, USA

Science Spotlight: HIV and Inflammation

"Extracellular Vesicles From the Cells Harboring HIV Defective Provirus Initiate Inflammatory Cascade" by Hongyan Sui Frederick National Laboratory for Cancer Research, Frederick, MD, USA

Science Spotlight: HIV and Inflammation

"Extracellular Vesicles’ miRNAs Correlate With Inflammatory Markers in Tanzanians With HIV" by Mussa H. Bago Kumamoto University, Kumamoto, Japan

Science Spotlight: HIV Transmission Insights Through Phylogenetics

"Evolution of HIV-1 A6 Clusters in Poland Following Full-Scale Armed Conflict in Ukraine" by Karol Serwin Pomeranian Medical University, Szczecin, Poland

Science Spotlight: Immunity to SARS-CoV-2 and Other Viruses

"Torque Teno Virus: A Predictive Biomarker for SARS-CoV-2 Vaccine Response in Immunosuppressed People" by Gonzalo Cabrerizo Instituto de Investigaciones Biomédicas en Retrovirus y SIDA, Buenos Aires, Argentina

Science Spotlight: Long-Acting Injectable ART Implementation

"Impact of 6-Monthly ART Dispensing on Retention in Malawi: A Target Trial Emulation Study" by Khumbo Shumba Health Economics and Epidemiology Research Office, Johannesburg, South Africa

Science Spotlight: Other Comorbidities

"Validation of SCORE and OST for Osteoporosis Risk Estimation in People Aging With HIV in Peru" by Joselito Malca Hernandez Yale University, New Haven, CT, USA

Science Spotlight: Risks and Responses to ART

"Infants With HIV Starting ART Within 4 Months of Age Can Achieve Sustained Undetectable HIV-1 DNA" by Alfredo Tagarro Fundación para la Investigación Biomédica Hospital 12 de Octubre, Madrid, Spain

Symposium: Making Sense of Integrase Strand Transfer Inhibitor Failure and Resistance

"Dolutegravir Resistance: How Frequent Is It and How Will It Evolve?" by Nicaise Ndembi Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia

Symposium: Making Sense of Integrase Strand Transfer Inhibitor Failure and Resistance

"Dolutegravir Resistance: What Are the Implications for Antiretroviral Therapy Programs?" by Jeremy Nel University of Witwatersrand, Johannesburg, South Africa

Symposium: Making Sense of Integrase Strand Transfer Inhibitor Failure and Resistance

"Long-Acting InSTI Strategies: Understanding the Risks for Failure and Resistance" by Saye Khoo University of Liverpool, Liverpool, UK

Symposium: Making Sense of Integrase Strand Transfer Inhibitor Failure and Resistance

"Panel Discussion" by Brenda E. Crabtree Ramírez National Institute of Medical Science and Nutrition Salvador Zubiran, Mexico City, Mexico

Suzanne McCluskey Massachusetts General Hospital, Boston, MA, USA

Anna Turkova MRC Clinical Trials Unit at UCL, London, UK

Symposium: Pathogenesis of HIV in the Brain: The Final Frontier

"Multiomics in the Brain" by Howard Fox University of Nebraska, Omaha, NE, USA

Symposium: Pathogenesis of HIV in the Brain: The Final Frontier

"The Central Nervous System Reservoir: Impact for Cure and Ongoing Neuropathology" by Melissa Churchill Royal Melbourne Institute of Technology, Melbourne, Australia

Symposium: Pathogenesis of HIV in the Brain: The Final Frontier

"Emerging Role of T Cells in the Central Nervous System" by Lydie Trautmann Henry M Jackson Foundation, Bethesda, MD, USA

Symposium: Pathogenesis of HIV in the Brain: The Final Frontier

"Discussion with Audience Questions and Answers" by

Symposium: Putting People at the Center of Prevention: New Models of Delivery

"Session Overview" by Kwasi Torpey University of Ghana, Accra, Ghana

Symposium: Putting People at the Center of Prevention: New Models of Delivery

"Leveraging Private-Sector Pharmacies to Expand Reach of Biomedical HIV Prevention Interventions" by Katrina Ortblad Fred Hutchinson Cancer Center, Seattle, WA, USA

Symposium: Putting People at the Center of Prevention: New Models of Delivery

"Empowering Communities: A Peer-Based Model for Expanding Equitable Access to PrEP and PEP in Mexico" by Alaín Pinzón Vihve Libre, Mexico City, Mexico

Symposium: Putting People at the Center of Prevention: New Models of Delivery

"We’ll Come to You: A Mobile Clinic Preexposure Prophylaxis Delivery Model" by Elzette Rousseau Desmond Tutu HIV Foundation, Cape Town, South Africa

Symposium: Putting People at the Center of Prevention: New Models of Delivery

"Discussion with Audience Questions and Answers" by